On power, yes — all of them. Every one of the 65 audio interfaces in this database reaches 100 dB SPL on the Audio-Technica ATH-M50X, which needs 1.3 mW at its 38Ω.
Power is one of three questions and the one that goes wrong least often. The other two — whether the source’s output impedance leaves the frequency response alone, and whether you will hear its noise floor — are answered further down, separately, because a source can pass one and fail another.
The cheapest one that does reach it is the Zoom AMS-22 at $100, which delivers 17 mW into 38Ω — 11 dB of headroom over the 1.3 mW this headphone needs for 100 dB SPL.
100 dB SPL is a peak level, not a listening level. If you listen at 85 dB the same headphone needs 0.04 mW, which is 15 dB less, and the answer above changes for most of the category. The model page has the full ladder.
Under the one-eighth rule the Audio-Technica ATH-M50X wants a source below 4.75Ω. Of the 43 audio interfaces here that publish an output impedance, 15 are under it and 28 are not.
The furthest over is the Tascam US-2x2HR at 66Ω, which is 14× the ceiling. Above that threshold the source stops being a volume control and starts being part of the frequency response. The simulator shows what that looks like.
The other 22 publish nothing at all on this, so they are not on either side of that count. This site leaves them blank rather than assuming a figure.
Hiss depends on the source’s own noise floor and on how sensitive the headphone is. At 99.0 dB/mW and 38Ω, the Audio-Technica ATH-M50X turns one microvolt of source noise into about -7 dB SPL — and the threshold where that stops being noticeable in a quiet room is around 20 dB SPL.
The one audio interface here that publishes a noise figure stays below that threshold with this headphone.
The remaining 64 publish no noise figure, so they cannot be placed on either side.
| Source | Price | Into 38Ω | Output impedance | Hiss in these | Power verdict |
|---|---|---|---|---|---|
| Steinberg IXO22 | $119 | 38 mW | not published | not published | Comfortable |
| IK Multimedia AXE I/O ONE | $130 | 30 mW | <0.1 Ω | not published | Comfortable |
| PreSonus Studio 24c | $149 | 32 mW | not published | not published | Comfortable |
| Universal Audio Volt 1 | $149 | 73 mW | not published | not published | Comfortable |
| Steinberg UR24C | $194 | 95 mW | not published | not published | Comfortable |
| Audient iD4 MkII | $199 | 117 mW | not published | not published | Comfortable |
| PreSonus Quantum ES 2 | $199 | 89 mW | not published | not published | Comfortable |
| Steinberg UR22C | $199 | 14 mW | not published | not published | Comfortable |
| Universal Audio Volt 2 | $199 | 73 mW | not published | not published | Comfortable |
| MOTU M2 | $219 | 281 mW | not published | not published | Comfortable |
| SSL 2 MkII | $229 | 315 mW | 1 Ω | not published | Comfortable |
| Focusrite Vocaster Two | $250 | 25 mW | not published | not published | Comfortable |
Sorted by how many of the three questions the source answers well, then by price. A blank in a column is a blank in the manufacturer’s own documentation, not a zero.
The Audio-Technica ATH-M50X on other categories: desktop amplifiers · desktop DAC/amps.
The Audio-Technica ATH-M50X page has every source in the database against this headphone, and the matcher takes your own numbers.