Will a desktop amplifier drive the Etymotic ER2SE?

On power, yes — all of them. Every one of the 69 desktop amplifiers in this database reaches 100 dB SPL on the Etymotic ER2SE, which needs 2.5 mW at its 15Ω.

Power is one of three questions and the one that goes wrong least often. The other two — whether the source’s output impedance leaves the frequency response alone, and whether you will hear its noise floor — are answered further down, separately, because a source can pass one and fail another.

Whether it gets loud enough

The cheapest one that does reach it is the JDS Labs Atom+ (2nd gen) at $99, which delivers 469 mW into 15Ω — 23 dB of headroom over the 2.5 mW this headphone needs for 100 dB SPL.

100 dB SPL is a peak level, not a listening level. If you listen at 85 dB the same headphone needs 0.08 mW, which is 15 dB less, and the answer above changes for most of the category. The model page has the full ladder.

Whether it changes how they sound

Under the one-eighth rule the Etymotic ER2SE wants a source below 1.88Ω. Of the 49 desktop amplifiers here that publish an output impedance, 45 are under it and 4 are not.

The furthest over is the Bottlehead Crack (OTL kit) at 120Ω, which is 64× the ceiling. Above that threshold the source stops being a volume control and starts being part of the frequency response. The simulator shows what that looks like.

The other 20 publish nothing at all on this, so they are not on either side of that count. This site leaves them blank rather than assuming a figure.

Whether you will hear it between tracks

Hiss depends on the source’s own noise floor and on how sensitive the headphone is. At 96.0 dB/mW and 15Ω, the Etymotic ER2SE turns one microvolt of source noise into about -6 dB SPL — and the threshold where that stops being noticeable in a quiet room is around 20 dB SPL.

Of the 21 desktop amplifiers here that publish a noise figure, 21 stay below that threshold with this headphone and 0 cross it.

The remaining 48 publish no noise figure, so they cannot be placed on either side.

The 12 best matches in this category

SourcePriceInto 15ΩOutput impedanceHiss in thesePower verdict
JDS Labs Atom+ (2nd gen)$99469 mW0.7 Ω0 dB SPLComfortable
Schiit Magni Heresy$992.6 W0.25 Ωnot publishedComfortable
Fosi Audio SK02$10089 mWnot publishednot publishedComfortable
Schiit Magni+$109938 mWnot publishednot publishedComfortable
Schiit Magni Unity$1192.8 W0.1 Ωnot publishedComfortable
JDS Labs Atom Amp 2$1291.2 W0.7 Ω-3 dB SPLComfortable
Schiit Vali 2+$149703 mW1.8 Ωnot publishedComfortable
Schiit Vali 3$149703 mW0.5 Ωnot publishedComfortable
Topping L30 II$1493.3 W0.1 Ω-16 dB SPLComfortable
PreSonus HP4$15033 mWnot publishednot publishedComfortable
SMSL HO100$1602.8 W<0.1 Ω-3 dB SPLComfortable
xDuoo MT-604$169938 mWnot publishednot publishedComfortable

Sorted by how many of the three questions the source answers well, then by price. A blank in a column is a blank in the manufacturer’s own documentation, not a zero.

The same headphone, other kinds of source

The Etymotic ER2SE on other categories: USB dongles · portable players · desktop DAC/amps · audio interfaces.

The Etymotic ER2SE page has every source in the database against this headphone, and the matcher takes your own numbers.